Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/10064
SEOM clinical guidelines for the management of germ cell testicular cancer (2016)
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ISSN: 1699-048X
eISSN: 1699-3055
WOS ID: 000389970300005
Scopus EID: 2-s2.0-84994268334
PMID: 27815687
Embase PUI: L613131025
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2016-12Document type
research articleCitation
Aparicio J., Terrasa Pons Josefa, Duran I., Germa-Lluch J. R., Girones R., Gonzalez-Billalabeitia E., et al. SEOM clinical guidelines for the management of germ cell testicular cancer (2016). Clin Transl Oncol. 2016 Dec;18(12):1187-1196. Epub 2016 Nov 4.Abstract
Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin-based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease.
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https://dx.doi.org/10.1007/s12094-016-1566-1MeSH
Neoplasm StagingMale
Young Adult
Neoplasms, Germ Cell and Embryonal
Spain
Adult
Testicular Neoplasms
Risk Factors
Humans
Adolescent
Practice Guidelines as Topic
DeCS
Guías de Práctica Clínica como AsuntoFactores de Riesgo
Humanos
Adulto Joven
Estadificación de Neoplasias
Neoplasias Testiculares
Adulto
Neoplasias de Células Germinales y Embrionarias
España
Adolescente
Masculino
This item appears in following Docusalut collections
Hospital Universitario Son Espases - HUSE > Comunicación científicaInstituto de Investigación Sanitaria Islas Baleares - IDISBA > Comunicación científica