Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/11135
How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry
Identifiers
DOI: 10.1093/jrr/rru022
ISSN: 0449-3060
eISSN: 1349-9157
WOS ID: 000342223100021
Scopus EID: 2-s2.0-84908155004
PMID: 24722683
Embase PUI: L605507452
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2014-09Document type
research articleCitation
Sabater S, Berenguer R, Honrubia-Gomez P, Rivera M, Nunez A, Jimenez-Jimenez E, et al. How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry. J Radiat Res. 2014 Sep;55(5):1009-14. Epub 2014 Apr 10.Abstract
Radiation of experimental culture cells on plates with various wells can cause a risk of underdosage as a result of the existence of multiple air-water interfaces. The objective of our study was to quantify this error in culture plates with multiple wells. Radiation conditions were simulated with the GAMOS code, based on the GEANT4 code, and this was compared with a simulation performed with PENELOPE and measured data. We observed a slight underdosage of similar to 4% on the most superficial half of the culture medium. We believe that this underdosage does not have a significant effect on the dose received by culture cells deposited in a monolayer and adhered to the base of the wells.
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https://dx.doi.org/10.1093/jrr/rru022Keywords
Monte Carloplate irradiation
culture cells
MeSH
Cell Culture TechniquesAbsorption, Radiation
Cell Physiological Phenomena
Equipment Design
Monte Carlo Method
Animals
Humans
Models, Statistical
Air
Equipment Failure Analysis
Scattering, Radiation
Computer Simulation
DeCS
Modelos EstadísticosAnimales
Simulación por Computador
Análisis de Falla de Equipo
Humanos
Aire
Fenómenos Fisiológicos Celulares
Absorción de Radiación
Diseño de Equipo
Dispersión de Radiación
Método de Montecarlo
Técnicas de Cultivo de Célula
This item appears in following Docusalut collections
Hospital Universitario Son Espases - HUSE > Comunicación científicaInstituto de Investigación Sanitaria Islas Baleares - IDISBA > Comunicación científica