Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/11711
Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain
Identifiers
ISSN: 1330-0962
eISSN: 1846-7482
WOS ID: 000514284400007
Scopus EID: 2-s2.0-85076527555
PMID: 31839724
Embase PUI: L2003765625
Share
Statistics
Item usage statisticsMetadata
Show Dublin Core item recordPublication date
2020-02Document type
research articleCitation
Garcia-Del-Pino I, Bauca JM, Gomez C, Caballero A, Llopis MA, Ibarz M, et al. Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain. Biochem Medica. 2020 Feb;30(1):10704. Epub 2019 Dec 15.Abstract
Introduction: Diabetes mellitus (DM) is one of the most prevalent diseases worldwide. The objective of this study was to find out under what pre-analytical conditions routine and diagnostic glucose tests are performed across Spanish laboratories; and also what criteria are used for DM diagnosis. Materials and methods: An online survey was performed by the Commission on Quality Assurance in the Extra-Analytical Phase of the Spanish Society of Laboratory Medicine (SEQC-ML). Access to the questionnaire was available on the home page of the SEQC-ML website during the period April-July 2018. Data analysis was conducted with the IBM SPSS (c) Statistics (version 20.0) program. Results: A total of 96 valid surveys were obtained. Most laboratories were in public ownership, serving hospital and primary care patients, with high and medium workloads, and a predominance of mixed routine-urgent glucose testing. Serum tubes were the most used for routine glucose analysis (92%) and DM diagnosis (54%); followed by lithium-heparin plasma tubes (62%), intended primarily for urgent glucose testing; point-ofcare testing devices were used by 37%; and plasma tubes with a glycolysis inhibitor, mainly sodium fluoride, by 19%. Laboratories used the cut-off values and criteria recognized worldwide for DM diagnosis in adults and glucose-impaired tolerance, but diverged in terms of fasting plasma glucose and gestational DM criteria. Conclusion: Preanalytical processing of routine and DM diagnostic glucose testing in Spain does not allow a significant, non-quantified influence of glycolysis on the results to be ruled out. Possible adverse consequences include a delay in diagnosis and possible under-treatment.
Publisher version
https://dx.doi.org/10.11613/BM.2020.010704MeSH
Blood Specimen CollectionBlood Glucose
Diabetes Mellitus
Pre-Analytical Phase
Spain
Humans
Laboratories, Hospital
Surveys and Questionnaires
DeCS
Diabetes MellitusHumanos
Glucemia
Laboratorios de Hospital
Fase Preanalítica
Encuestas y Cuestionarios
Recolección de Muestras de Sangre
España