Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/12154
Treatment of Intracranial Aneurysms With the SILK Embolization Device in a Multicenter Study. A Retrospective Data Analysis
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ISSN: 0148-396X
eISSN: 1524-4040
WOS ID: 000410732500017
Scopus EID: 2-s2.0-85041453544
PMID: 28327963
Embase PUI: L620749224
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2017-10Document type
research articleCitation
Manuel Pumar J, Banguero A, Cuellar H, Guimaraens L, Masso J, Miralbes S, et al. Treatment of Intracranial Aneurysms With the SILK Embolization Device in a Multicenter Study. A Retrospective Data Analysis. Neurosurgery. 2017 Oct;81(4):595-601.Abstract
BACKGROUND: Flow-diverter technology has become an important stent-based embolization tool in the treatment of complex cerebrovascular pathology. We report here the experience of 4 Spanish centers with using the SILK flow-diverter (SFD) device. OBJECTIVE: To evaluate the safety and efficacy of using the SFD in the endovascular treatment of intracranial aneurysms with complex morphology. METHODS: We retrospectively examined a prospectively maintained database of patients treated with SFD devices between July 2008 and December 2013 at 1 of 4 institutions in Spain. Data regarding patient demographics, aneurysm characteristics, and technical procedure were analyzed. Angiographic and clinical findings were recorded during the procedure and at 12 months postoperatively. RESULTS: A total of 175 SFD devices were implanted in 157 patients (women/men: 119/38; mean, median, and range of age: 56.2, 56.7, and 19-80 years, respectively), who were treated in a delayed manner (3-6 months from the event) for 180 aneurysms (165 unruptured and 15 ruptured). Adverse events (acute and delayed) were observed in 28.7% of cases (45/157), and most were resolved (19.1%; 30/157). Six months after the procedure, total morbidity and mortality were 9.6% (15/157) and 3.2% (5/157), respectively. Long-term imaging follow-up showed complete occlusion, neck remnants, and residual aneurysm in 78.1% (100/128), 14.0% (18/128), and 7.8% (10/128) of cases, respectively. CONCLUSIONS: The SFD device is an effective tool for the treatment of challenging aneurysms, and allows complete occlusion within a year of the procedure in most patients, with morbidity and mortality comparable to those previously reported for similar devices.
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https://dx.doi.org/10.1093/neuros/nyw123MeSH
AgedAdult
Embolization, Therapeutic
Humans
Intracranial Aneurysm
Cerebral Angiography
Middle Aged
Male
Prospective Studies
Databases, Factual
Female
Treatment Outcome
Retrospective Studies
Statistics as Topic
DeCS
Resultado del TratamientoEstadística como Asunto
Bases de Datos Factuales
Femenino
Masculino
Aneurisma Intracraneal
Humanos
Persona de Mediana Edad
Embolización Terapéutica
Estudios Prospectivos
Angiografía Cerebral
Anciano
Estudios Retrospectivos
Adulto