Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/12565
Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
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eISSN: 1479-5868
WOS ID: 000511416400002
Scopus EID: 2-s2.0-85077208493
PMID: 31870449
Embase PUI: L630286001
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Galmes-Panades, Aina M.; Varela-Mato, Veronica; Konieczna, Jadwiga








Publication date
2019-12-23Document type
research articleCitation
Galmes A, Varela-Mato V, Konieczna J, Warnberg J, Martinez-Gonzalez MA, Salas-Salvado J, et al. Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study. Int J Behav Nutr Phys Act. 2019 Dec 23;16(1):137.Abstract
Background: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Methods: This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55-75 years, BMI 27-40 Kg/m(2)) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had >= 3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Results: Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides, and higher body muscle mass and HDL cholesterol (all p-values < 0.05). Conclusions: Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health.
Publisher version
https://dx.doi.org/10.1186/s12966-019-0892-4Keywords
Inactive timeLight physical activity
Moderate to vigorous physical activity
Time in bed
Cardiometabolic risk
Isotemporal substitution
MeSH
Diabetes Mellitus, Type 2Metabolic Syndrome
Triglycerides
Aged
Humans
Middle Aged
Cross-Sectional Studies
Obesity
United Kingdom
Male
Accelerometry
Time Factors
Sedentary Behavior
Cholesterol, HDL
Female
Risk Factors
Adiposity
Sleep
Waist Circumference
Exercise
Retrospective Studies
DeCS
SueñoEjercicio Físico
Conducta Sedentaria
Síndrome Metabólico
Factores de Tiempo
Femenino
HDL-Colesterol
Masculino
Circunferencia de la Cintura
Estudios Transversales
Factores de Riesgo
Reino Unido
Humanos
Persona de Mediana Edad
Obesidad
Acelerometría
Anciano
Diabetes Mellitus Tipo 2
Triglicéridos
Estudios Retrospectivos
Adiposidad
This item appears in following Docusalut collections
Hospital Universitario Son Espases - HUSE > Comunicación científicaAtención Primaria de Mallorca - APMALL > Comunicación científica
Instituto de Investigación Sanitaria Islas Baleares - IDISBA > Comunicación científica