Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/12620
A multinational observational study identifying primary care patients at risk of overestimation of asthma control
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eISSN: 2055-1010
WOS ID: 000502995200001
Scopus EID: 2-s2.0-85075991978
PMID: 31804501
Embase PUI: L630061203
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Kritikos, Vicky; Price, David; Papi, Alberto; Infantino, Antonio; Stallberg, Bjorn; Ryan, Dermot; Lavorini, Federico; Chrystyn, Henry; Haughney, John; Lisspers, Karin; Gruffydd-Jones, Kevin; Roman-Rodriguez, Miguel

Publication date
2019-12-05Document type
research articleCitation
Kritikos V, Price D, Papi A, Infantino A, Stallberg B, Ryan D, et al. A multinational observational study identifying primary care patients at risk of overestimation of asthma control. NPJ Prim Care Respir Med. 2019 Dec 05;29:43.Abstract
Factors related to the discrepancy between patient-perceived and actual disease control remain unclear. Identifying patients at risk of overestimation of asthma control remains elusive. This study aimed to (i) investigate the relationship between patient-reported and actual level of asthma control (ii), compare the characteristics between patients who believe their asthma is well controlled that accurately report 'well-controlled' asthma with those that do not, and (iii) identify factors associated with inaccurately reported 'well-controlled' asthma. A historical, multinational, cross-sectional study using data from the iHARP (initiative Helping Asthma in Real-life Patients) review service for adults with asthma prescribed fixed-dose combination therapy. Data from 4274 patients were analysed. A major discrepancy between patient-reported and Global Initiative for Asthma defined asthma control was detected; 71.1% of patients who reported 'well-controlled' asthma were inaccurate in their perception despite receiving regular maintenance therapy. Significant differences were noted in age, gender, body mass index, education level, medication use, side effects, attitudes to preventer inhaler use, inhaler technique review and respiratory specialist review between patients who accurately reported 'wellcontrolled' asthma and those who did not. Independent risk factors associated with inaccurately reported 'well-controlled' asthma were: having taken a maximum of 5-12 puffs or more of reliever inhaler on at least one day within the previous 4 weeks; being female; having seen a respiratory specialist more than a year ago (rather than in the previous year); and having required oral corticosteroids for worsening asthma in the previous year. The study highlighted the significant hidden burden associated with under-recognition of poor asthma control, on the part of the patient and the need for targeted interventions designed to address the continuing discrepancy between perceived and actual disease control.
Publisher version
https://dx.doi.org/10.1038/s41533-019-0156-4MeSH
AsthmaSpain
Adrenal Cortex Hormones
Humans
Drug Therapy, Combination
France
Netherlands
Bronchodilator Agents
Middle Aged
Cross-Sectional Studies
United Kingdom
Norway
Sweden
Male
Administration, Inhalation
Anti-Asthmatic Agents
Female
Treatment Outcome
Primary Health Care
Incidence
DeCS
IncidenciaResultado del Tratamiento
Antiasmáticos
Femenino
Suecia
Noruega
Administración por Inhalación
Masculino
Estudios Transversales
Reino Unido
Broncodilatadores
Quimioterapia Combinada
Francia
Humanos
Persona de Mediana Edad
Países Bajos
Asma
Corticoesteroides
Atención Primaria de Salud
España
This item appears in following Docusalut collections
Atención Primaria de Mallorca - APMALL > Comunicación científicaInstituto de Investigación Sanitaria Islas Baleares - IDISBA > Comunicación científica