Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/15186
Breastfeeding Disparities between Multiples and Singletons by NICU Discharge
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DOI: 10.3390/nu11092191
eISSN: 2072-6643
WOS ID: 000487964600210
Scopus EID: 2-s2.0-85072551491
PMID: 31547239
Embase PUI: L2002546138
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2019-09Document type
research articleCitation
Porta R, Capdevila E, Botet F, Ginovart G, Moliner E, Nicolas M, et al. Breastfeeding Disparities between Multiples and Singletons by NICU Discharge. Nutrients. 2019 Sep;11(9):2191.Abstract
Multiple pregnancy increases the risk of a range of adverse perinatal outcomes, including breastfeeding failure. However, studies on predictive factors of breastfeeding duration in preterm twin infants have a conflicting result. The purpose of this observational study was to compare feeding practices, at hospital discharge, of twin and singleton very low birth weight infants. The study is part of a prospective survey of a national Spanish cohort of very low birth weight infants (SEN1500) that includes 62 neonatal units. The study population comprised all infants registered in the network from 2002 to 2013. They were grouped into singletons and multiples. The explanatory variables were first analyzed using univariate models; subsequently, significant variables were analyzed simultaneously in a multiple stepwise backward model. During the twelve-year period, 32,770 very low birth weight infants were included in the database, of which 26.957 were discharged alive and included in this analysis. Nine thousand seven hundred and fifty-eight neonates were multiples, and 17,199 were singletons. At discharge, 31% of singleton infants were being exclusively breastfed, 43% were bottle-fed, and 26% were fed a combination of both. In comparison, at discharge, only 24% of multiple infants were exclusively breastfed, 43% were bottle-fed, and 33% were fed a combination of both (p < 0.001). On multivariable analysis, twin pregnancy had a statistically significant, but small effect, on cessation of breastfeeding before discharge (OR 1.10; 95% CI: 1.02, 1.19). Risks of early in-hospital breastfeeding cessation were also independently associated with multiple mother-infant stress factors, such as sepsis, intraventricular hemorrhage, retinopathy, necrotizing enterocolitis, intubation, and use of inotropes. Instead, antibiotic treatment at delivery, In vitro fertilization and prenatal steroids were associated with a decreased risk for shorter in-hospital breastfeeding duration. Multiple pregnancy, even in the absence of pathological conditions associated to very low birth weight twin infants, may be an impeding factor for in-hospital breastfeeding.
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https://dx.doi.org/10.3390/nu11092191MeSH
PregnancyBreast Feeding
Twins
Infant, Very Low Birth Weight
Infant, Newborn
Intensive Care Units, Neonatal
Prospective Studies
Adult
Female
Humans
Patient Discharge
Infant, Premature
DeCS
HumanosEstudios Prospectivos
Embarazo
Lactancia Materna
Recién Nacido
Unidades de Cuidado Intensivo Neonatal
Femenino
Gemelos
Recien Nacido Prematuro
Adulto
Alta del Paciente
Recién Nacido de muy Bajo Peso
This item appears in following Docusalut collections
Hospital Universitario Son Espases - HUSE > Comunicación científicaAtención Primaria de Mallorca - APMALL > Comunicación científica
Instituto de Investigación Sanitaria Islas Baleares - IDISBA > Comunicación científica