Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/15524
A multi-center, randomized, clinical trial comparing adhesive polyurethane foam dressing and adhesive hydrocolloid dressing in patients with grade II pressure ulcers in primary care and nursing homes
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ISSN: 1471-2296
WOS ID: 000332044700001
Scopus EID: 2-s2.0-84890517611
PMID: 24359122
Embase PUI: L373495280
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2013-12-21Document type
research articleCitation
Guillen-Sola M, Soler Mieras A, Tomas-Vidal AM, GAUPP-Expert Panel. A multi-center, randomized, clinical trial comparing adhesive polyurethane foam dressing and adhesive hydrocolloid dressing in patients with grade II pressure ulcers in primary care and nursing homes. BMC Fam Pract. 2013 Dec 21;14:196.Abstract
Background: Pressure ulcers (PrUs) are ischemic wounds in the skin and underlying tissues caused by long-standing pressure force over an external bone or cartilaginous surface. PrUs are an important challenge for the overall health system because can prolong patient hospitalization and reduce quality of life. Moreover, 95% of PrUs are avoidable, suggesting they are caused by poor quality care assistance. PrUs are also costly, increasing national costs. For example, they represent about 5% of overall annual health expenses in Spain. Stages I and II PrUs have a combined prevalence of 65%. According main clinical guidelines, stage II PrUs (PrU-IIs) are usually treated by applying special dressings (polyurethane or hydrocolloid). However, little scientific evidence regarding their efficacy has been identified in scientific literature. Our aim is to assess the comparative efficacy of adhesive polyurethane foam and hydrocolloid dressings in the treatment of PrU-IIs in terms of healed ulcer after 8 weeks of follow-up. Methods/design: This paper describes the development and evaluation protocol of a randomized clinical trial of two parallel treatment arms. A total of 820 patients with at least 1 PrU-II will be recruited from primary health care and home care centers. All patients will receive standardized healing procedures and preventive measures (e.g. positional changes and pressure-relieving support surfaces), following standardized procedures. The main outcome will be the percentage of wounds healed after 8 weeks. Secondary outcomes will include cost-effectiveness, as evaluated by cost per healed ulcer and cost per treated patient and safety evaluated by adverse events. Discussion: This trial will address the hypothesis that hydrocolloid dressings will heal at least 10% more stage II PrUs and be more cost-effective than polyurethane foam dressings after 8 weeks.
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https://dx.doi.org/10.1186/1471-2296-14-196Keywords
Pressure ulcersPressure sore
Hydrocolloid dressing
Polyurethane foam dressings
Healing process
MeSH
BandagesAdhesives
Aged
Young Adult
Pressure Ulcer
Adult
Humans
Nursing Homes
Middle Aged
Wound Healing
Male
Severity of Illness Index
Female
Polyurethanes
Treatment Outcome
Bandages, Hydrocolloid
Primary Health Care
DeCS
Resultado del TratamientoFemenino
Cicatrización de Heridas
Masculino
Vendas Hidrocoloidales
Humanos
Persona de Mediana Edad
Casas de Salud
Adulto Joven
Adhesivos
Anciano
Vendajes
Índice de Severidad de la Enfermedad
Úlcera por Presión
Atención Primaria de Salud
Adulto
Poliuretanos