Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/17011
Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients: Part II. Treatment
Identifiers
ISSN: 0342-4642
eISSN: 1432-1238
WOS ID: 000263160600005
Scopus EID: 2-s2.0-59849102023
PMID: 18972100
Embase PUI: L50316848
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2009-02Document type
review articleCitation
Guery Benoit P, Arendrup MC, Auzinger G, Azoulay E, Borges Sa M, Johnson EM, et al. Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients: Part II. Treatment. Intensive Care Med. 2009 Feb;35(2):206-14. Epub 2008 Oct 30.Abstract
Invasive candidiasis and candidemia are frequently encountered in the nosocomial setting particularly in the intensive care unit (ICU). To review the current management of invasive candidiasis and candidemia in non-neutropenic adult ICU patients based on a review of the literature and an European expert panel discussion. Empiric and directed treatment for invasive candidiasis are predicated on the hemodynamic status of the patient. Unstable patients may benefit from broad-spectrum antifungal agents, which can be narrowed once the patient has stabilized and the identity of the infecting species is established. In stable patients, a more classical approach using fluconazole may be satisfactory provided that the patient is not colonized with fluconazole resistant strains or there has been recent past exposure to an azole (< 30 days). In contrast, pre-emptive therapy is based on the presence of surrogate markers.
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https://dx.doi.org/10.1007/s00134-008-1339-6Keywords
AntifungalAzole
Candida
Candidiasis
Echinocandins
Invasive candidiasis
Intensive care
Polyenes
MeSH
BacteremiaAmphotericin B
Fluconazole
Intensive Care Units
Antifungal Agents
Humans
Candida albicans
Candidiasis
DeCS
Candida albicansCandidiasis
Humanos
Fluconazol
Anfotericina B
Bacteriemia
Antifúngicos
Unidades de Cuidados Intensivos