Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/17134
A Proposed Approach to Chronic Airway Disease (CAD) Using Therapeutic Goals and Treatable Traits: A Look to the Future
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DOI: 10.2147/COPD.S263430
ISSN: 1178-2005
WOS ID: 000565661800001
Scopus EID: 2-s2.0-85091265225
PMID: 32943862
Embase PUI: L2005015314
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Perez de Llano, Luis; Miravitlles, Marc; Golpe, Rafael; Javier Alvarez-Gutierrez, Francisco; Cisneros, Carolina; Almonacid, Carlos; Martinez-Moragon, Eva; Gonzalez-Barcala, Francisco-Javier; Ramos-Barbon, David; Plaza, Vicente; Luis Lopez-Campos, Jose; Pablo de-Torres, Juan; Casanova, Ciro; Garcia Rivero, Juan Luis; Rodriguez Hermosa, Juan; Calle Rubio, Myriam; Jose Soler-Cataluna, Juan; Cosio, Borja G

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2020Document type
research articleCitation
Perez De Llano L, Miravitlles M, Golpe R, Alvarez-Gutierrez FJ, Cisneros C, Almonacid C, et al. A Proposed Approach to Chronic Airway Disease (CAD) Using Therapeutic Goals and Treatable Traits: A Look to the Future. Int J Chronic Obstr Pulm Dis. 2020;15:2091-100.Abstract
Chronic airflow obstruction affects a wide range of airway diseases, the most frequent of which are asthma, COPD, and bronchiectasis; they are clearly identifiable in their extremes, but quite frequently overlap in some of their pathophysiological and clinical characteristics. This has generated the description of new mixed or overlapping disease phenotypes with no clear biological grounds. In this special article, a group of experts provides their perspective and proposes approaching the treatment of chronic airway disease (CAD) through the identification of a series of therapeutic goals (TG) linked to treatable traits (TT) - understood as clinical, physiological, or biological characteristics that are quantifiable using biomarkers. This therapeutic approach needs validating in a clinical trial with the strategy of identification of TG and treatment according to TT for each patient independently of their prior diagnosis.
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https://dx.doi.org/10.2147/COPD.S263430This item appears in following Docusalut collections
Hospital Universitario Son Espases - HUSE > Comunicación científicaInstituto de Investigación Sanitaria Islas Baleares - IDISBA > Comunicación científica