Identifier to cite or link to this item: http://hdl.handle.net/20.500.13003/17398
Air pollutant exposure during pregnancy and fetal and early childhood development. Research protocol of the INMA [Childhood and Environment Project]
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DOI: 10.1157/13101050
ISSN: 0213-9111
WOS ID: 000253953500012
Scopus EID: 2-s2.0-34249780140
PMID: 17419934
Embase PUI: L46851364
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Esplugues, Ana; Fernandez-Patier, Rosalia; Aguilera, Inma; Inigueza, Carmen; Garcia Dos Santos, Saul; Aguirre Alfaro, Amelia; Lacasana, Marina; Estarlich, Marisa; Grimalt, Joan O.; Fernandez, Marieta; Rebagliato, Marisa; Sala, Maria; Tardon, Adonina; Torrent Quetglas, Maties

Publication date
2007-03Document type
research articleCitation
Esplugues A, Fernandez-Patier R, Aguilera I, Inigueza C, Garcia Dos Santos S, Aguirre Alfaro A, et al. Air pollutant exposure during pregnancy and fetal and early childhood development. Research protocol of the INMA [Childhood and Environment Project]. Gac Sanit. 2007 Mar;21(2):162-71.Abstract
Introduction: The INMA (INfancia y Medio Ambiente (Spanish for Environment and Childhood]) project is a cooperative research network. This project aims to study the effects of environment and diet on fetal and early childhood development. This article aims to present the air pollutant exposure protocol during pregnancy and fetal and early childhood development of the INMA project. Methods: The information to assess air pollutant exposure during pregnancy is based on outdoor measurement of air pollutants (nitrogen dioxide [NO2], volatile organic compounds [VOC], ozone, particulate matter [PM10, PM2.5] and of their composition (polycyclic aromatic hydrocarbons]); measurement of indoor and personal exposure (VOC and NO2); urinary measurement of a biological marker of hydrocarbon exposure (1-hydroxypyrene); and data gathered by questionnaires and geographic information systems. These data allow individual air pollutant exposure indexes to be developed, which can then be used to analyze the possible effects of exposure on fetal development and child health. Conclusion: This protocol and the type of study allow an approximation to individual air pollutant exposure to be obtained. Finally, the large number of participants (N = 4,000), as well as their geographic and social diversity, increases the study's potential.
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https://dx.doi.org/10.1157/13101050MeSH
PregnancyInfant, Newborn
Child Development
Female
Inhalation Exposure
Maternal Exposure
Humans
Child, Preschool
Fetal Development
Air Pollution
Infant
DeCS
Contaminación del AirePreescolar
Humanos
Desarrollo Fetal
Exposición Materna
Embarazo
Desarrollo Infantil
Recién Nacido
Femenino
Exposición por Inhalación
Lactante